Gene therapy to lower cholesterol

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This week we will talk about cholesterol, the molecule that causes so much damage in the population, and how gene therapy, the use of genes as a therapeutic tool, may be the great solution that we were all waiting to face … First of all, it should be noted that cholesterol is an essential component ... Read more

Western Blot Protocols (part 3) – Antibody Incubation & Gel Visualization

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1. Blocking Visualization of proteins in membranes (non-compulsory): As an non-compulsory step, we will confirm the protein had been transferred efficiently by staining the membrane with ponceau purple. Incubate the membrane in ponceau for five minutes and wash with water till the bands are clear. After verification, the bands can then be destained by persevering with ... Read more

Protocols – Western Transfer (Western Blot)

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Western Transfer, also called Western Blotting, is a fast immunoblotting method for figuring out the presence of a specific protein in a fancy combination of proteins similar to cell lysates or sera. The method exploits each the effectivity of SDS-PAGE to separate a mix of proteins into distinct protein bands, and the flexibility of immunochemical ... Read more
Misrepresentation and distortion of research in biomedical literature.

Misrepresentation and distortion of research in biomedical literature.

Publication in peer-reviewed journals is an important step in the scientific course of. However, publication will not be merely the reporting of info arising from an easy evaluation thereof. Authors have broad latitude when writing their reviews and could also be tempted to consciously or unconsciously “spin” their examine findings. Spin has been outlined as ... Read more
Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations.

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations.

Recently, NIH has funded a middle for autophagy analysis named the Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence, situated at the University of New Mexico Health Science Center (UNM HSC), with aspirations to advertise autophagy analysis regionally, nationally, and internationally. The middle has three main missions: (i) to help junior college of ... Read more
Translating innovation in biomedical research: Design and delivery of a competency-based regulatory science course.

Translating innovation in biomedical research: Design and delivery of a competency-based regulatory science course.

As the tempo of biomedical innovation quickly evolves, there’s a want to coach researchers to know regulatory science challenges related to medical translation. We describe a pilot course aimed toward addressing this want delivered collectively by means of the Mayo Clinic Center for Clinical and Translational Science and the Yale-Mayo Center for Excellence in Regulatory ... Read more

StressMarq

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VPS35 Promotion Dates: March 1st– April 30th, 2020 StressMarq is pleased to offer 20% off our retail price on VPS35 Antibodies, for a total of 50% off our retail price, AND an extra 25% off our VPS35 ELISA Kit. Filtered VPS35 Products: https://www.stressmarq.com/?post_type=product&s=vps35&v=3e8d115eb4b3

17α-hydroxylase

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The anti-androgenic effect of chronic exposure to semicarbazide on male Japanese flounder (Paralichthys olivaceus) and its potential mechanisms. Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP September/23/2018 Semicarbazide (SMC), a new marine pollutant, has anti-estrogenic effects on female Japanese flounder (Paralichthys olivaceus). However, whether SMC also affects the reproductive endocrine system of male ... Read more

E

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Estradiol 17α-dehydrogenase publication: Renwick, A.G.C. and Engel, L.L. The partial purification of 17α- and 17β-estradiol dehydrogenase activities from chicken liver. Biochim. Biophys. Acta 146 (1967) 336–348. I would apprecitate any, even unpublished or indirect information about this enzyme. (EC 1.1.1.148) 17β-Hydroxysteroid Dehydrogenase Type 12 is Responsible for Maturation-Inducing Steroid Synthesis During Oocyte Maturation in Nile ... Read more
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