Category: Recombinant

Binding of naturally occurring anti-DNA antibodies to estradiol.

Binding of naturally occurring human anti-DNA autoantibodies to beta-estradiol and native DNA has been investigated. Sera from seven SLE sufferers had been examined for his or her reactivity with beta-estradiol and native calf thymus DNA. Solid Phase enzyme immunoassay was carried...

Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.

Subtle modulation of antibody-binding properties by protein engineering usually lies with an correct structural and energetic description of how an antigen is recognised. Thus, with the intent to extend the affinity and add a bias in favour of pure estradiol in...