Category: Translating innovation in biomedical research: Design and delivery of a competency-based regulatory science course.

Binding of naturally occurring anti-DNA antibodies to estradiol.

Binding of naturally occurring human anti-DNA autoantibodies to beta-estradiol and native DNA has been investigated. Sera from seven SLE sufferers had been examined for his or her reactivity with beta-estradiol and native calf thymus DNA. Solid Phase enzyme immunoassay was carried...

Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.

Subtle modulation of antibody-binding properties by protein engineering usually lies with an correct structural and energetic description of how an antigen is recognised. Thus, with the intent to extend the affinity and add a bias in favour of pure estradiol in...

Translating innovation in biomedical research: Design and delivery of a competency-based regulatory science course.

As the tempo of biomedical innovation quickly evolves, there’s a want to coach researchers to know regulatory science challenges related to medical translation. We describe a pilot course aimed toward addressing this want delivered collectively by means of the Mayo Clinic...